2nd Semester, Academic Year 2010-2011
Mode: 3-Hour Lecture per Week (1.5 Hours per Session)
Faculty-in-Charge: Prof. Manolito E. Bambase Jr. (Sections W and X)
Download the Course Requirements and Policies
The course is an introduction to the application of chemical engineering principles to biochemical systems. It is an integration of the concepts from various areas of knowledge such as microbiology, biochemistry, mass and energy balances, reaction kinetics, fluid dynamics, transport phenomena and separation processes for the purpose of analyzing biochemical systems and designing bioreactors.
Course Prerequisites: MCB 1, CHEM 160, CHE 149, and CHE 152
Lecture Topics
LECTURE 1.Review of Microbiological Concepts ( Download Lecture Notes )
Cellular Types and Structure; Microbial, Plant and Animal Cell CulturesLECTURE 2. Biomolecule: Chemicals for Life ( Download Lecture Notes )
Carbohydrates Proteins; Lipids, and Nucleic AcidsLECTURE 3. Metabolic Stoichiometry and Energetics ( Download Lecture Notes )
Overview of Cellular Metabolism; Cellular Stoichiometry: Elemental Balance, Yields Concepts, and Metabolic Heat of ReactionLECTURE 4. Enzymes: Kinetics and Applications ( Download Lecture Notes )
Enzyme Structure, Classification, and Nomenclature; Enzyme Kinetics and Activity; Enzyme Immobilization TechniquesLECTURE 5. Kinetics of Cell Cultures ( Download Lecture Notes )
Substrate Utilization, Product and Biomass Formation, and Inhibitory Effect; Thermal Death KineticsLECTURE 6. Design and Analysis of Biological Reactors
Types of Biological Reactors; Gas-Liquid Mass Transfer and AgitationDownload Lecture 6A
Download Lecture 6B
Download Lecture 6C
LECTURE 7. Bioprocess Separations: Recovery of Biological Products
Recovery of Particulates, Product Isolation, and Product Recovery Trains ( Download Lecture Notes )
Reference Textbooks
Biochemical Engineering (2nd Edition)
by James Lee
Biochemical Engineering Fundamentals (2nd Edition)
by James E. Bailey and David F. Ollis
